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Symbol
Name
ID
Il7
interleukin 7
MGI:96561
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Abnormality of the immune system
Seborrheic dermatitis
Pustule
Recurrent skin infections
Disease(s) Associated with IL7
epidermodysplasia verruciformis

Mouse Phenotypes
immune system phenotype
decreased thymus weight
small thymus
thymus hypoplasia
decreased thymocyte number
abnormal B cell differentiation
increased pro-B cell number
arrested B cell differentiation
abnormal double-negative T cell morphology
decreased double-negative T cell number
decreased B cell number
increased pre-B cell number
abnormal T cell subpopulation ratio
decreased NK T cell number
decreased T cell number
decreased single-positive T cell number
decreased lymphocyte cell number
decreased leukocyte cell number
abnormal B cell morphology
abnormal CD8-positive, alpha beta T cell morphology
abnormal myeloid leukocyte morphology
decreased spleen weight
small spleen
spleen hypoplasia
abnormal NK T cell physiology
absent Peyer's patches
abnormal mesenteric lymph node morphology
absent mesenteric lymph nodes
small lymph nodes
lymph node hypoplasia
absent axillary lymph nodes
absent cervical lymph nodes
small inguinal lymph nodes
absent popliteal lymph nodes
absent lymph nodes
blepharitis
skin inflammation
Availability Mouse Genotype
Il7hlb368/Il7hlb368
Il7m1Jyen/Il7m1Jyen
Il7tm1.1Mysl/Il7tm1.1Mysl *
Il7tm1Dnax/Il7tm1Dnax
Il7tm1Hms/Il7tm1Hms
Tg(KRT14-Il7)1Tsk/Tg(KRT14-Il7)1Tsk
Il7tm1.1Mysl/Il7+
Tg(H2-Ea-Il7)10Rhdr/0
Tg(KRT14-Il7)1Tsk/0
Il7tm2.1Iku/Il7tm2.1Iku
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory